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GSK-3β (human), (recombinant) (GST-tag)

 
BML-SE355-0005 5 µg 265.00 USD
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Replaces Prod. #: ADI-PPK-425

Product Specification

Alternative Name:Glycogen synthase kinase 3β
 
MW:73 kDa
 
Source:Produced in insect cells. Full length human glycogen synthase kinase-3ß is fused at the N-terminus to a GST-tag.
 
UniProt ID:P49841
 
Application Notes:Useful for Useful for kinetic and functional studies, phosphorylation of target substrates, drug screening.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:GSK-3β, a serine/threonine kinase, is involved in many cell functions, including, insulin, growth factor and nutrient signaling, cell division, apoptosis, modulation of transcription factors AP-1 and CREB, and specification of cell fate. Phosphorylation of GSK-3β on serine 9 results in its inactivation. GSK-3β has also been shown to phosphorylate tau, the major component of neurofibrillary lesions of Alzheimer’s disease.
 
Technical Info/Product Notes:Replacement for ADI-PPK-425
 

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