Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

S1P receptor 1 (rat), (membrane preparation)

 
BML-SE327-0050 50 assays 706.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:EDG-1
 
Source:Cell membrane preparation from Rh7777 cell line transfected to overexpress S1P (EDG-1) receptor.
 
UniProt ID:P48303
 
Application Notes:Can be used for GTP-γ-[35S] binding assays using sphingosine-1-phosphate (SL-140) as the receptor ligand.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Scientific Background:S1P belongs to a family of G protein-coupled receptors whose ligands are lysophospholipids. There are 8 known members of the lysophospholipid receptor (EDG) family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. The ligand for S1P is sphingosine-1-phosphate. Lysophospholipid receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. S1P is expressed in cardiovascular, leukocyte containing and other tissues.
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
S1P receptor
By biological activity:
S1P receptor Native protein
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Product Flyers
Exclusive Sphingosine Kinase 1 Inhibitor
Exclusive Sphingosine Kinase 1 Inhibitor
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,