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14-3-3γ (human), (recombinant) (GST-tag)

BML-SE313-0100 100 µg 299.00 USD
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Product Specification

MW:~60 kDa
Source:Produced in E. coli. Human 14-3-3γ is fused at the N-terminus to a GST-tag.
UniProt ID:P61981
Formulation:Liquid. In 50mM TRIS/HCl, pH 7.5, 150mM NaCl.
Purity:≥90% (SDS-PAGE)
Purity Detail:Purified by multi-step chromatography.
Application Notes:Can be used for protein-protein interaction studies and gel overlays.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:14-3-3 proteins are dimeric phosphoserine/phosphothreonine binding proteins, which have been shown to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation-state, stability, transcription, metabolism, and malignant transformation. Potential 14-3-3 γ protein–protein interactions are also differentially regulated by cytokine stimulation. One report showed that 14-3-3 γ expression is induced in arterial trauma by cytokines, which suggests that this protein may play an important role in progression of vascular proliferative diseases.

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