Product Details
| Alternative Name: | Sphingomyelin cholinephosphohydrolase |
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| Source: | Isolated from Staphylococcus aureus. |
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| CAS: | 9031-54-3 |
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| UniProt ID: | P09978 |
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| Formulation: | Liquid. Supplied in 50% glycerol/0.25 M phosphate buffer. |
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| Specific Activity: | Specific activity: 100-300 U/mg protein. One unit will hydrolyze 1 µmol of TNPAL-sphingomyelin per minute at pH 7.4 and 37°C |
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| Application Notes: | May be used exogenously to initiate the sphingomyelin signaling pathway. Has very little activity on phosphatidylcholine. |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Acid sphingomyelinase promotes SGK1-dependent vascular calcification: T. Luong, et al.; Clin. Sci.
135, 515 (2021),
Abstract;
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