Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Neuropeptide Y1 receptor polyclonal antibody

BML-SA642-0050 50 µl 322.00 USD
BML-SA642-0200 200 µl 550.00 USD
Do you need bulk/larger quantities?

Product Specification

Alternative Name:NPY1R
Immunogen:Synthetic peptide corresponding to aa 237-252 of human NPY1R (neuropeptide Y1 receptor).
UniProt ID:P25929
Species reactivity:Human, Rat
Applications:ICC, IHC, WB
Blocking Peptide:Included: Neuropeptide Y1 Receptor Control Peptide (40µg). Supplied lyophilized.
Purity Detail:Affinity purified IgG.
Formulation:Lyophilized from PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
Reconstitution:To lyophilized antibody, add 50µl or 200µl (depending on which size was purchased) of deionized water. To lyophilized peptide, add 100µl of deionized water.
Use/Stability:Lyophilized antibody and lyophilized peptide can be stored intact at room temperature for several weeks. For longer periods they should be stored at -20°C. After reconstitution, the antibody solution can be stored at 4°C for up to 2 weeks. For longer periods, small aliquots should be stored at -20°C or below.Centrifuge all antibody preparations before use (10,000 X g for 5 minutes). After reconstitution, control peptide should be stored at -20°C.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:The NPY receptors belong to the G protein-coupled receptor superfamily. Activation of these receptors by NPY affects [Ca2+]i, adenylate cyclase, and a number of ion channels. NPY1R is considered to be a postsynaptic receptor. In the CNS, NPY1Rs are concentrated in the cortical areas of the brain, cerebral cortex, olfactory nucleus, hippocampus, hypothalamic nuclei, and thalamic nuclei. In addition, this receptor has a bimodal role in the immune system, serving as a strong negative regulator on T cells, as well as an activator of antigen-presenting cell function.
Technical Info/Product Notes:PREADSORPTION CONTROL: 1µg peptide per 1µg antibody. Prepare 2 tubes. In the first, dilute the necessary amount of antibody in 200-500µl of PBS, 1% BSA and 0.025% sodium azide. Prepare the second tube identically to the first with the addition of the appropriate amount of peptide. Incubate at room temperature for 1 hr. Centrifuge both tubes at 10,000Xg for 5 min. Use the supernatants from tubes 1 and 2 for parallel experiments.
Neuropeptide Y1 receptor polyclonal antibody Western blot
Western blot analysis of Jurkat cells (lanes 1, 4); K562 cells (lanes 2, 5); RBL cells (lanes 3, 6); rat brain lysates (lanes 7, 8). Lanes 1, 2, 3, 7: Anti-NPY1R. Lanes 4, 5, 6, 8: Anti-NPY1R preincubated with the control peptide.
Please mouse over
Neuropeptide Y1 receptor polyclonal antibody Western blot

Product Literature References

Gene therapy mediated seizure suppression in Genetic Generalised Epilepsy: Neuropeptide Y overexpression in a rat model: K.L. Powell, et al.; Neurobiol. Dis. 113, 23 (2018), Abstract;
Neuropeptide Y receptor 1 is expressed by B and T lymphocytes and mast cells in infantile haemangiomas: E.M. Tan, et al.; Acta Paediatr. 106, 292 (2017), Abstract;

Product Toolbox


Certificate of Analysis


By target:
Neuropeptide Y receptor
By biological activity:
Neuropeptide Y receptor Polyclonal antibody
By catalog section:


Technical Service
Customer Service

Related Literature

Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Obesity Catalog
Obesity Catalog
Download as PDF

All new literature pieces

Recommend this page

For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,