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TRPV2 (extracellular) polyclonal antibody

 
BML-SA607-0050 50 µl 334.00 USD
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Product Specification

Alternative Name:Transient receptor potential cation channel subfamily V member 2
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to aa 413-428 of rat TRPV2.
 
UniProt ID:Q9WUD2
 
Species reactivity:Rat
 
Applications:ICC, IP, WB
 
Formulation:Lyophilized from PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Although it shares around 50% homology with TRPV1, TRPV2 is not activated by capsaicin or by protons. It has a high temperature threshold of ~52°C and is considered to play an essential role in the perception of high-intensity noxious heat stimulation. TRPV2 is also considered to be a stretch-activated channel and to play a role in skeletal and cardiac muscle degeneration and pain pathway. TRPV2 is expressed in DRG neurons, different brain regions and non-neuronal tissues such as spleen, lung and intestine and in components of the immune system.
 

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