HCN4, pAb



BML-SA600-0050	50 µl	300.00 USD

BML-SA600-0200	200 µl	469.00 USD

Hyperpolarization-activated cation currents (Ih) appear in the heart and the brain and play a crucial role in controlling electrical pacemaker activity, contributing to biological processes such as heartbeat, sleep-wake cycle and synaptic plasticity. The Ih currents are generated by the Hyperpolarization-activated Cyclic Nucleotide-gated channel family (HCN), which comprises four homologous members, HCN1-4. Each HCN subunit consists of six transmembrane (TM) domains, a pore region between TM5-TM6 and a cyclic nucleotide binding domain in the cytoplasmic C-terminus.

Alternative Name:	Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4

Formulation:	Lyophilized from PBS, pH 7.4, 1% BSA and 0.05% sodium azide.

Immunogen:	Recombinant human HCN4 (aa 119-155)

Source/Host:	From rabbit.

Specificity:	Recognizes mouse and rat HCN4.

Application:	Immunohistochemistry Western Blot

Long Term Storage:	-20°C

Background / Technical Information:	Please click here for the comprehensive product datasheet.