14-3-3τ/θ, pAb - Enzo Life Sciences

BML-SA481

Revised 01-Feb-10

14-3-3τ/θ, pAb
SYNONYMS	KCIP-1 Protein kinase C inhibitor protein 1 HS1 protein T cell protein
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	14-3-3 Proteins / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
BML-SA481-0025		25 µl	87.00 USD
BML-SA481-0100		100 µl	303.00 USD
Replaces Prod. #: ALX-215-028

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse Rat Sheep
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Neat serum containing sodium azide.
IMMUNOGEN:	Acetylated N-terminal epitope of 14-3-3 tau/theta.
SPECIFICITY:	Recognizes human, mouse, rat, cow and sheep 14-3-3τ/θ.
APPLICATION:	Immunohistochemistry (1:60) Western Blot (1:3’000) Optimal condition must be determined individually for each application.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C

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General Information

BACKGROUND/TECHNICAL INFORMATION
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General Literature References

Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein.: H. Martin et al.; FEBS Lett. 331, 296 (1993) Abstract
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies.: H. Martin et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain.: Y. Patel et al.; Biochim. Biophys. Acta. 1222, 405 (1994) Abstract
14-3-3 alpha and delta are the phosphorylated forms of raf-activating 14-3-3 beta and zeta. In vivo stoichiometric phosphorylation in brain at a Ser-Pro-Glu-Lys MOTIF.: A. Aitken et al.; J. Biol. Chem. 270, 5706 (1995) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins.: D.H. Jones et al.; FEBS Lett. 368, 55 (1995) Abstract
Expression and structural analysis of 14-3-3 proteins.: D.H. Jones et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation.: C.P. Wheeler-Jones et al.; Biochem. J. 315, 41 (1996) Abstract
Neurofibrillary tangles of Alzheimer’s disease brains contain 14-3-3 proteins.: R. Layfield et al.; Neurosci. Lett. 209, 57 (1996) Abstract
The structural basis for 14-3-3:phosphopeptide binding specificity.: M.B. Yaffe et al.; Cell 91, 961 (1997) Abstract
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain.: M. Matto-Yelin et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.: J. Wiltfang et al.; J. Neurochem. 73, 2485 (1999) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain.: H.C. Baxter et al.; Neuroscience 109, 5 (2002) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants.: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.: H-K. Chen et al.; Cell 113, 457 (2003) Abstract
Mammalian and yeast 14-3-3 isoforms form distinct patterns of dimers in vivo.: M. Chaudhri et al.; Biochem. Biophys. Res. Commun. 300, 679 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein.: P. Steinacker et al.; Mol. Cell Biol. 25, 1339 (2005) Abstract
Novel brain 14-3-3 interacting proteins involved in neurodegenerative disease.: S. Mackie & A. Aitken; FEBS J. 272, 4202 (2005) Abstract

Further Categories Containing This Product:

Polyclonal Antibodies