14-3-3β, pAb - Enzo Life Sciences

BML-SA474

Revised 01-Feb-10

14-3-3β, pAb
SYNONYMS	KCIP-1 Protein kinase C inhibitor protein 1 Protein 1054 14-3-3α
PRODUCT LINE	Signal Transduction
PRODUCT CATEGORY	14-3-3 Proteins / Related Products

Ordering Information

Product Numbers:	Format:	Size:	Unit Price:	Quantity:	Add To Cart
BML-SA474-0025		25 µl	87.00 USD
BML-SA474-0100		100 µl	303.00 USD
Replaces Prod. #: ALX-215-021

Product Specification

SPECIES CROSSREACTIVITY:	Human Mouse Rat Sheep Others
SOURCE/HOST:	From rabbit.
FORMULATION:	Liquid. Neat serum.
IMMUNOGEN:	Acetylated N-terminal domain of 14-3-3 β.
SPECIFICITY:	Recognizes human, mouse, rat, bovine, sheep 14-3-3β. Is highly specific for the β isoform.
APPLICATION:	Affinity Chromatography ELISA Immunohistochemistry (1:600) Western Blot (HRP/ECL detection (1:3’000)) Optimal conditions must be determined individually for each application.
SHIPPING:	SHIPPED ON BLUE ICE
LONG TERM STORAGE:	-20°C

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Product Specific Literature References

Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein: H. Martin, et al.; FEBS Lett. 331, 296 (1993) Abstract; Full Text
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodies: H. Martin, et al.; J. Neurochem. 63, 2259 (1994) Abstract
Purification of 14-3-3 protein and analysis of isoforms in chicken brain: Y. Patel, et al.; Biochim. Biophys. Acta 1222, 405 (1994) Abstract
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins: D.H. Jones, et al.; FEBS Lett. 368, 55 (1995) Abstract; Full Text
Expression and structural analysis of 14-3-3 proteins: D.H. Jones, et al.; J. Mol. Biol. 245, 375 (1995) Abstract
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation: C.P. Wheeler-Jones, et al.; Biochem. J. 315, 41 (1996) Abstract; Full Text
14-3-3 inhibits the Dictyostelium myosin II heavy-chain-specific protein kinase C activity by a direct interaction: identification of the 14-3-3 binding domain: M. Matto-Yelin, et al.; Mol. Biol. Cell 8, 1889 (1997) Abstract; Full Text
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease: J. Wiltfang, et al.; J. Neurochem. 73, 2485 (1999) Abstract
Functional specificity in 14-3-3 isoform interactions through dimer formation and phosphorylation. Chromosome location of mammalian isoforms and variants: A. Aitken; Plant Mol. Biol. 50, 993 (2002) Abstract
Immunolocalisation of 14-3-3 isoforms in normal and scrapie-infected murine brain: H.C. Baxter, et al.; Neuroscience 109, 5 (2002) Abstract
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1: H.K. Chen, et al.; Cell 113, 457 (2003) Abstract
Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein: P. Steinacker, et al.; Mol. Cell. Biol. 25, 1339 (2005) Abstract; Full Text

General Information