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BACE1 polyclonal antibody

 
BML-SA465-0100 100 µg 260.00 USD
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Product Specification

Alternative Name:BACE, β-Secretase, β-Site APP cleaving enzyme 1, Memapsin-2, Aspartyl protease 2
 
Host:Rabbit
 
Immunogen:Synthetic peptide corresponding to the catalytic domain of human BACE1 (BACE, ß-secretase).
 
UniProt ID:P56817
 
Species reactivity:Human, Mouse, Rat
 
Crossreactivity:Does not cross-react with BACE2.
 
Applications:WB
 
Formulation:Liquid. In PBS containing 0.05% sodium azide and 50% glycerol.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:BACE1 is expressed as a pre-pro-aspartyl protease, sometimes glycosylated, and inserted into the cell membrane as a dimer with catalytic domains in the cytosol. It is implicated in angiogenesis and Alzheimer’s disease.
 

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