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SIRT2 (human) polyclonal antibody

BML-SA444-0100 100 µl 329.00 USD
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Product Specification

Alternative Name:Sirtuin-2
Immunogen:Recombinant human SIRT2.
UniProt ID:Q8IXJ6
Source:From rabbit serum.
Species reactivity:Human
Specificity:Recognizes native and recombinant SIRT2.
Crossreactivity:Does not cross-react with other sirtuins tested (SIRTs 1, 3 and 5).
Formulation:Liquid. Immunodepleted antiserum diluted in PBS
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Dry Ice
Long Term Storage:-80°C
Scientific Background:A complex comprising HDAC6 and SIRT2 colocalizes with the microtubule network and both enzymes can deacetylate a-tubulin lysine-40 in purified tubulin heterodimers or microtubules. SIRT2 protein levels rise during mitosis and it becomes phosphorylated. Overexpression of SIRT2 delays exit of cells from mitosis, suggesting that it may play a role in cell cycle regulation.

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For Research Use Only. Not for use in diagnostic procedures.
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