Replaces Prod. #: ALX-210-222
Product Details
| Alternative Name: | Poly(ADP-ribose) polymerase, PARP-1 |
| |
| Host: | Rabbit |
| |
| Immunogen: | Synthetic peptide corresponding to aa 509-524 of bovine PARP automodification domain. |
| |
| UniProt ID: | P18493 |
| |
| Source: | Whole rabbit serum. |
| |
| Species reactivity: | Human, Mouse, Rat
Bovine
|
| |
| Applications: | ELISA, WB
|
| |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000, colorimetric). Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application |
| |
| Application Notes: | Detects a band of ~116kDa by Western blot. |
| |
| Formulation: | Liquid. Neat serum containing 0.05% sodium azide. |
| |
| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
| |
| Shipping: | Dry Ice |
| |
| Long Term Storage: | -20°C |
| |
| Regulatory Status: | RUO - Research Use Only |
| |
Western Blot Analysis of the Poly(ADP-ribose) polymerase, pAb (BML-SA253). Lane 1: Molecular Weight Marker, Lane 2: Human HL60 Cell Extract (BML-SW101).
Please mouse over
Product Literature References
Structure-Activity Relationship of Hydroxycinnamic Acid Derivatives for Cooperating with Carnosic Acid and Calcitriol in Acute Myeloid Leukemia Cells: A. Trachtenberg, et al.; Biomedicines
9, 1517 (2021),
Abstract;
Synergistic cytotoxicity of methyl 4-hydroxycinnamate and carnosic acid to acute myeloid leukemia cells via calcium-dependent apoptosis induction: A. Trachtenberg, et al.; Front. Pharmacol.
10, 507 (2019),
Application(s): Western-blot,
Abstract;
Full Text
Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting: S. Pesakhov, et al.; Oncotarget
7, 31847 (2016),
Application(s): Western-blot,
Abstract;
Full Text
Gestational diabetes mellitus alters apoptotic and inflammatory gene expression of trophobasts from human term placenta: T.R. Magee, et al.; J. Diabetes Complications
28, 448 (2014),
Application(s): Western-blot,
Abstract;
Full Text
Increased PARP-1 association with DNA in alkylation damaged, PARP-inhibited mouse fibroblasts: P.S. Kedar, et al.; Mol. Cancer Res.
10, 360 (2012),
Application(s): Western-blot,
Abstract;
Full Text
General Literature References
Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly (ADP-ribose) polymerase.: P.J. Duriez; Biochim. Biophys Acta
1334, 65 (1997),
Abstract;
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE.: Y.A. Lazebnik et al.; Nature
371, 346 (1994),
Abstract;
Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study.: D. Lamarre et al.; Biochim. Biophys. Acta
950, 147 (1988),
Abstract;
Related Products
