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Poly(ADP-ribose) monoclonal antibody

 
BML-SA216-0100 100 µl 385.00 USD
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Product Specification

Alternative Name:PAR
 
Clone:not available
 
Host:Mouse
 
Isotype:IgG3
 
Immunogen:Purified poly(ADP-ribose) polymer (chain length of 2-50 units).
 
Species reactivity:Species independent
 
Applications:ELISA, ICC, IP, WB
 
Recommended Dilutions/Conditions:Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Purified from mouse ascites.
 
Formulation:Liquid. In PBS containing 50% glycerol.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

Product Literature References

PARP-1/2 Inhibitor Olaparib Prevents or Partially Reverts EMT Induced by TGF-β in NMuMG Cells: M. Schacke, et al.; Int. J. Mol. Sci. 20, 518 (2019), Abstract; Full Text
Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair: X. Kong, et al.; J. Cell Sci. 131, jcs219311 (2018), Abstract;
PARP Inhibition Prevents Ethanol-Induced Neuroinflammatory Signaling and Neurodegeneration in Rat Adult-Age Brain Slice Cultures: N. Tajuddin, et al.; J. Pharmacol. Exp. Ther. 365, 117 (2018), Abstract; Full Text
Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization: L. Mc Gurk, et al.; Mol. Cell 71, 703 (2018), Abstract;
P-Glycoprotein Inhibition Sensitizes Human Breast Cancer Cells to Proteasome Inhibitors: R.R. Deshmukh, et al.; J. Cell. Biochem. 118, 1239 (2017), Abstract;
Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model: L.I. Hughes, et al.; PeerJ 5, e3318 (2017), Abstract; Full Text
Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites: G.M. Saquilabon Cruz, et al.; Nucleic Acids Res. 44, e27 (2016), Abstract; Full Text
Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis: J. Yu, et al.; BMC Gastroenterol. 16, 81 (2016), Application(s): Western blot analysis of PARP activation, Abstract; Full Text
Alcohol-induced One-carbon Metabolism Impairment Promotes Dysfunction of DNA Base Excision Repair in Adult Brain: A.K. Fowler, et al.; J. Biol. Chem. 21, 287 (2012), Abstract; Full Text
Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells: J.H. Kupper, et al.; J. Biol. Chem. 265, 18721 (1990), Abstract;
Rapid assay of poly(ADP-ribose) glycohydrolase: L. Menard & G.G. Poirier; Biochem. Cell Biol. 65, 668 (1987), Abstract;
Monoclonal antibodies to poly(adenosine diphosphate ribose) recognize different structures: H. Kawamitsu, et al.; Biochemistry 23, 3771 (1984), Abstract;

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The PARP Family & ADP Ribosylation
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