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U-18666A

Oxido-squalene cyclase inhibitor
 
BML-S200-0010 10 mg 98.00 USD
 
BML-S200-0050 50 mg 397.00 USD
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A useful tool for inhibition of cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum. Inhibits cholesterol transport in a variety of cell types such as macrophages and sympathetic neurons. May be used to induce a Neimann-Pick disease type C (NPC)or NPC-like phenotype in a variety of cell types. Inhibits cholesterol biosynthesis at the level of oxido-squalene cyclase (OSC). Induction of cataracts is a common toxic feature of OSC inhibitors such as U18666A.

Product Specification

Alternative Name:3β-(2-Diethylaminoethoxy)-Androstenone . HCl
 
Formula:C25H41NO2 . HCl
 
MW:424.1
 
CAS:3039-71-2
 
Purity:≥99% (TLC)
 
Appearance:White solid.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
BML-S200 structure
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BML-S200 structure

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