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Deoxynojirimycin

Glucosidase inhibitor
 
BML-S110-0001 1 mg 33.00 USD
 
Replaces Prod. #: ALX-580-003

Inhibits α-glucosidase I and II.

Product Specification

Formula:C6H13NO4
 
MW:163.2
 
CAS:19130-96-2
 
Purity:≥98% (TLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White solid.
 
Solubility:Soluble in water (25mg/ml).
 
Long Term Storage:-20°C
 
580-003
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580-003

Product Literature References

Glycosidase inhibitors as potential HIV entry inhibitors?: I. Robina et al.; Curr. Drug. Metab. 5, 329 (2004), Abstract;
The alpha-glucosidase inhibitor 1-deoxynojirimycin blocks human immunodeficiency virus envelope glycoprotein-mediated membrane fusion at the CXCR4 binding step: M.J. Papandreou et al.; Mol Pharmacol 61, 186 (2002), Abstract;
Deoxynojirimycin: synthesis and biological activity: A.B. Hughs & A.J. Rudge ; Nat. Prod. Rep. 11, 135 (1994), Abstract;
Identification of a novel mechanism for the removal of glucose residues from high mannose-type oligosaccharides: K. Suh et al.; J. Biol. Chem. 267, 21671 (1992), Abstract;
Inhibitors of oligosaccharide processing: U. Furhmann et al.; Biochim Biophys Acta 825, 95 (1985), Abstract;
Characterization of Bacillus subtilis DSM704 and its production of 1-deoxynojirimycin: D.C. Stein et al.; Appl. Environ. Microbiol. 48, 280 (1984), Abstract;
Inhibition of N-linked oligosaccharide trimming does not interfere with surface expression of certain integral membrane proteins: B. Burke et al.; Embo J. 3, 551 (1984), Abstract;
Purification by affinity chromatography of glucosidase I, an endoplasmic reticulum hydrolase involved in the processing of asparagine-linked oligosaccharides: H. Hettkamp et al.; Eur. J. Biochem. 142, 85 (1984), Abstract;
1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes: V. Gross et al.; J. Biol. Chem. 258, 12203 (1983), Abstract;
Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins: N. Peyrieras et al.; Embo J. 823, 823 (1983), Abstract;

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