Product Details
Alternative Name: | Proteasome subunit α type-4, Macropain subunit C9, Proteasome subunit L |
|
Clone: | MCP257 |
|
Host: | Mouse |
|
Isotype: | IgG2b |
|
Immunogen: | Human placenta derived proteasomes. |
|
UniProt ID: | P25789 |
|
Gene/Protein Identifier: | PSMA4 (gene name) |
|
Source: | Purified from hybridoma tissue culture supernatant. |
|
Species reactivity: | Human, Mouse, Rat Rabbit
|
|
Specificity: | Recognizes the α3 subunit of the 20S proteasome. |
|
Applications: | IHC, WB
|
|
Purity Detail: | Partially purified ascites. |
|
Formulation: | Liquid. In PBS containing 10mM sodium azide. |
|
Handling: | Avoid freeze/thaw cycles. |
|
Shipping: | Blue Ice |
|
Long Term Storage: | -20°C |
|
Technical Info/Product Notes: | Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from "standard" nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins. |
|
Regulatory Status: | RUO - Research Use Only |
|
Product Literature References
Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro: S.K. Shin, et al.; Exp. Mol. Med.
49, e287 (2017),
Abstract;
Full Text
Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis: F. Cerruti, et al.; Sci. Rep.
7, 17626 (2017),
Abstract;
Full Text
Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation: W.H. Choi, et al.; Nat. Commun.
7, 10963 (2016),
Application(s): Western blot,
Abstract;
Related Products