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Proteasome 20S α7 subunit monoclonal antibody (MCP72)

 
BML-PW8110-0025 25 µl 118.00 USD
 
BML-PW8110-0100 100 µl 345.00 USD
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Product Specification

Alternative Name:Proteasome subunit α type-3, Macropain subunit C8
 
Clone:MCP72
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Dinitrophenylated human placenta derived proteasomes.
 
UniProt ID:P25788
 
Gene/Protein Identifier:PSMA3 (gene name)
 
Species reactivity:Human, Rat
Arthropod, Rabbit, Yeast
 
Specificity:Recognizes the α7 subunit of the 20S proteasome.
 
Applications:IHC, WB
 
Purity Detail:Partially purified ascites.
 
Formulation:Liquid. In PBS containing 10mM sodium azide.
 
Handling:Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from "standard" nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.
 

Product Literature References

Denervation-Induced Activation of the Ubiquitin-Proteasome System Reduces Skeletal Muscle Quantity Not Quality: C.W. Baumann, et al.; PLoS One 11, e0160839 (2016), Application(s): Western blot, left soleus muscles, Abstract; Full Text
Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation: W.H. Choi, et al.; Nat. Commun. 7, 10963 (2016), Application(s): Western blot, Abstract;
Time-Course of Muscle Mass Loss, Damage, and Proteolysis in Gastrocnemius following Unloading and Reloading: Implications in Chronic Diseases: A. Chacon-Cabrera, et al.; PLoS One 11, e0164951 (2016), Application(s): Immunoblotting of 1D electrophoresis, frozen mouse muscle samples, Abstract; Full Text
Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure: D.S. Pitcher, et al.; EBioMedicine 2, 642 (2015), Application(s): Western Blot, Abstract;
p53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53: H. Yan, et al.; Cell Death Dis. 6, e1662 (2015), Application(s): Western Blotting, Abstract; Full Text

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