Sp100 (human), pAb



BML-PW0325-0025	25 µl	90.00 USD

BML-PW0325-0100	100 µl	312.00 USD

Sp100 is an interferon-inducible protein and a major constituent of distinct nuclear domains, known as nuclear dots (NDs) or PML bodies. NDs play a role in autoimmunity, virus infections, and in the etiology of acute promyelocytic leukaemia. SUMO modification of Sp100 has been shown to promote interaction of Sp100 with non-histone chromosomal proteins, suggesting a regulatory role in chromatin organization and in functional interplay between these nuclear bodies and chromatin.

Product Specification

Formulation:	Liquid. In PBS containing 0.01% sodium azide.

Immunogen:	Synthetic peptide corresponding to aa 292-304 of human Sp100.

Source/Host:	From rabbit.

Specificity:	Recognizes human Sp100 and SUMO modified Sp100 species.

Application:	Immunocytochemistry Western Blot

Long Term Storage:	-20°C

Background / Technical Information:	Please click here for the comprehensive product datasheet.