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RWJ-60475 (AM)3

CD45 inhibitor
 
BML-PR110-0001 1 mg 152.00 USD
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RWJ-60475-(AM)3 is a cell-permeable acetoxymethyl (AM) ester of RWJ-60475. The AM esters confer cell membrane permeability and are hydrolyzed by intracellular esterases, trapping the active inhibitor within the cell. The IC50 for the hydrolyzed, active inhibitor is 2 µM.

Product Specification

Formula:C22H23BrNO13P
 
MW:620.4
 
Purity:≥95% (HPLC)
 
Appearance:Pale yellow-brown oil.
 
Solubility:Soluble in DMSO (25 mg/ml), acetone, or dimethylchloride.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Make solutions fresh daily.
 
Handling:Protect from moisture.
 
BML-PR110 structure
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BML-PR110 structure

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