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PF-356231

MMP inhibitor
 
BML-PI155-0001 1 mg 104.00 USD
 
BML-PI155-0005 5 mg 404.00 USD
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Specific non-chelating small-molecule inhibitor of MMP-12 (IC50 = 14 nM). At higher concentrations it inhibits other MMPs, but spares MMP-1, making it a valuable tool for investigation of MMP activity and function.

Product Specification

Formula:C25H20N2O3S
 
MW:428.5
 
CAS:766536-21-4
 
Purity:≥98% (TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO (25mg/ml).
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
BML-PI155 structure
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BML-PI155 structure

Product Literature References

MMP-7 mediates cleavage of N-cadherin and promotes smooth muscle apoptosis: H. Williams, et al.; Cardiovasc. Res. 87, 137 (2010), Abstract; Full Text

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MMP
MMP-12
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MMP Inhibitor
MMP-12 Inhibitor
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