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Argatroban

Thrombin inhibitor
 
BML-PI146-0010 10 mg 113.00 USD
 
BML-PI146-0050 50 mg 470.00 USD
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Argatroban is a synthetic peptidomimetic thrombin inhibitor which is in clinical use. It presents significant advantages as an anticoagulant in deep vein thrombosis, stroke prevention in atrial fibrillation and thromboembolic disease and especially in patients with coronary artery disease and heparin-induced thrombocytopenia.

Product Specification

Formula:C23H36N6O5S
 
MW:508.6
 
CAS:74863-84-6
 
Purity:≥98% (HPLC)
 
Identity:Determined by NMR and LCMS.
 
Appearance:White to off-white powder.
 
Solubility:Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
PI-146 Argatroban web
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Product Literature References

Nafamostat mesilate improves function recovery after stroke by inhibiting neuroinflammation in rats: C. Li, et al.; Brain Behav. Immun. 56, 230 (2016), Application(s): Positive control, Abstract;
Nafamostat mesilate protects against acute cerebral ischemia via blood-brain barrier protection: J. Want, et al.; Neuropharmacology 105, 398 (2016), Application(s): Administered intravenously into rats, Abstract;
Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice: X. de la Rosa, et al.; Stroke 45, 1453 (2014), Application(s): Used in osmotic pump with rat brain samples, Abstract;

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