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BML-PI145 Revised 05-Mar-10
Apstatin
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PRODUCT LINE Signal Transduction
PRODUCT CATEGORY Aminopeptidases / Related Products
Ordering Information
Product Numbers: Format: Size: Unit Price: Quantity: Add To Cart
BML-PI145-0001   1 mg 73.00 USD Add To Cart
Product Specification
SEQUENCE: N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-prolyl-L-prolyl-L-alaninamide
MW: 459.5
CAS NUMBER: 160470-73-5
PURITY: 95%
APPEARANCE: Lyophilized solid.
SOLUBILITY: Soluble in water (>25 mg/mL) and DMSO (20 mg/mL).
SHIPPING: SHIPPED ON BLUE ICE
LONG TERM STORAGE: -20°C
Product Description
Apstatin is a potent and selective inhibitor of aminopeptidase P (APP), Ki=2.6 µM for purified rat lung membrane-bound APP. It blocks the APP-mediated degradation of bradykinin. Limits myocardial infarct size alone or with ACE inhibitors.
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