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Boc-Gly-Val-Val-CHO

γ-secretase inhibitor
 
BML-PI128-0005 5 mg 115.00 USD
 
BML-PI128-0025 25 mg 417.00 USD
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A novel substrate-based (γ-40 site) aldehyde inhibitor of γ-secretase. In whole cells overexpressing amloid ß protein precursor, Boc-GVV-CHO dose-dependently inhibited amyloid ß cleavage. γ-secretase is an important therapeutic target for strategies designed to lower amyloid ß production.

Product Specification

Alternative Name:Boc-GVV-CHO
 
Sequence:Boc-GVV-CHO
 
Formula:C17H31N3O5
 
MW:357.5
 
Source:Synthetic.
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO (>25 mg/ml) or ethanol (10 mg/ml warm).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
 
BML-PI128 structure
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BML-PI128 structure

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