Irreversible inhibitor of chymotrypsin-like serine proteases such as granzyme D. Inhibits LPS-induced expression of COX-2 in macrophages. Inhibits γ-irradiation-induced apoptosis in myeloid leukemic cells.
Product Details
| Alternative Name: | Nα-Tosyl-Phe-chloromethylketone |
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| Sequence: | Na-Tosyl-Phe-chloromethylketone |
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| MW: | 351.8 |
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| CAS: | 402-71-1 |
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| Purity: | ≥98% (TLC) |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Calcium-Independent Phospholipase A2β Is Dispensable in Inflammasome Activation and Its Inhibition by Bromoenol Lactone: L. Franchi, et al.; J. Innate Immun.
1, 607 (2009),
Application(s): WB of mouse bone marrow cells,
Abstract;
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