Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

NNGH

MMP inhibitor
 
BML-PI115-0005 5 mg 62.00 USD
 
BML-PI115-0025 25 mg 251.00 USD
 
Potent inhibitor of human stromelysin-1 (MMP-3), Ki=0.13 µM. Also inhibits MMP-1, MMP-2, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 (metalloelastase), MMP-13, MMP-14, and MMP-20.

Product Specification

Alternative Name:N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid
 
Formula:C13H20N2O5S
 
MW:316.4
 
CAS:161314-17-6
 
Purity:≥99% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (30mg/ml) or 100% ethanol (8mg/ml).
 
Long Term Storage:Ambient
 
BML-PI115 v2
Please mouse over
BML-PI115 v2

Product Literature References

Catalytic domain of MMP20 (Enamelysin) - the NMR structure of a new matrix metalloproteinase: Y. Arendt et al.; FEBS Lett. 581, 4723 (2007), Abstract;
A high-affinity carbohydrate-containing inhibitor of matrix metalloproteinases: V. Calderone; Chem. Med. Chem 1, 598 (2006), Abstract;
Crystal structure of the catalytic domain of human matrix metalloproteinase 10: I. Bertini et al.; J. Mol. Biol. 336, 707 (2004), Abstract;
Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastase: A. Y. Jeng et al.; Bioorg. Med. Chem. Lett. 8, 897 (1998), Abstract;
Discovery of CGS 27023A, a non-peptidic, potent, and orally active stromelysin inhibitor that blocks cartilage degradation in rabbits: L. J. MacPherson et al.; J. Med. Chem. 40, 2525 (1997), Abstract;
NNGH is a potent inhibitor of MMPs: Unpublished data, BIOMOL Internatinal, LP; (0),

Product Toolbox

PRODUCT RESOURCES

Print as PDF
MSDS
Certificate of Analysis

RELATED PRODUCTS

By catalog section:
By biological activity:
MMP Inhibitor

PRODUCT SUPPORT

Technical Service
Bulk Quantity Quote
Customer Service

Related Literature

Scientific Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling 20-Sep-10
Download as PDF

All new literature pieces

Recommend this page

 
Keep in touch

©2014 Enzo Life Sciences, Inc.,