Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

L-α-Phosphatidylinositol-3,4-P2

Activator of PKC and Akt
 
BML-PH106-0100 100 µg 161.00 USD
Do you need bulk/larger quantities?
 
Replaces Prod. #: ALX-307-038

Activates Ca2+-insensitive PKC isotypes δ, ε and η. Activates Akt/PKB by direct interaction with the Akt PH domain.

Product Specification

Formula:C41H76O19P3 . 5NH4
 
MW:966.0 . 90.2
 
Purity:≥98% (NMR)
 
Appearance:White solid.
 
Solubility:Soluble in chloroform/methanol/water, 50:50:10 (10mg/ml); not water soluble but resuspends, with vigorous vortexing, to ~0.5 mg/ml in water. See references for method of incorporation into mixed lipid vesicles by sonication, and for dissolving in a detergent-containing buffer.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-20°C
 
Handling:Hygroscopic.
 
BML-PH106 structure
Please mouse over
BML-PH106 structure

Product Literature References

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate: T.F. Franke, et al.; Science 275, 665 (1997), Abstract;
Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains: J.K. Klarlund, et al.; Science 275, 1927 (1997), Application(s): Dissolving in a detergent-containing buffer., Abstract;
Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3: A. Toker, et al.; J. Biol. Chem. 269, 32358 (1994), Application(s): Method of incorporation into mixed lipid vesicles, Abstract;

Related Literature

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,