Replaces Prod. #: ALX-340-015
- Potent TP agonist
- Used in cardiovascular studies
- highly cited
U-46619 is a Prostaglandin H2/thromboxane A2 analog and a potent thromboxane A2 receptor (TP) agonist (EC50 = 0.035µM). U-46619 induces platelet shape change and aggregation at 32nM. U-46619 also activates p38 MAPK.
Product Details
| Alternative Name: | 9,11-Dideoxy-9α,11α-methanoepoxy prostaglandin F2α, 9,11-Dideoxy-9α,11α-methanoepoxy prosta5Z,13E-dien-1-oic acid |
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| Formula: | C21H34O4 |
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| MW: | 350.5 |
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| Source: | Synthetic. |
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| CAS: | 56985-40-1 |
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| Purity: | ≥98% (TLC) |
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| Identity: | Identity determined by 1H-NMR. |
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| Appearance: | Pale yellow oil. |
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| Solubility: | Soluble in DMF (100mg/ml), DMSO, 100% ethanol, DMSO, or PBS, pH 7.2 (2mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stable for at least 1 years after receipt when stored at -20°C. We do not recommend storing aqueous solutions for more than one day. |
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| Technical Info/Product Notes: | Note: Product is not sterile. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
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