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Prostaglandin I2 sodium

Prostanoid receptor ligand
 
BML-PG011-0001 1 mg 85.00 USD
 
BML-PG011-0010 10 mg 662.00 USD
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Biosynthesis in endothelial cells. Induces vasodilation, inhibits platelet aggregation by receptor-mediated stimulation of adenylate cyclase. Cytoprotective. Fibrinolytic. Half-life under physiological conditions is 2 minutes.

Product Specification

Alternative Name:PGI2 . Na
 
Formula:C20H31NaO5
 
MW:374.5
 
CAS:61849-14-7
 
Purity:≥98% (TLC)
 
Appearance:White solid.
 
Solubility:Soluble in basic buffer (unstable at neutral or acidic pH).  The higher the pH the more stable the compound will be, but for in vitro or in vivo use  pH ~9 is recommended.  Solubility at pH 9.0 is ~10mg/ml.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Aqueous solution at pH 9 can be used directly in cell or tissue culture. The effects of PGI2 are short lived and may require continuous infusion in order to observe a response.
 
Handling:PGI2 hydrolyzes rapidly to 6-Keto-PGF1α upon exposure to moisture in the air. Store the solid either dessicated or under inert gas.
 
BML-PG011 structure
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BML-PG011 structure

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