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Prostaglandin F

Prostanoid receptor ligand
 
BML-PG008-0002 2 mg 64.00 USD
 
BML-PG008-0010 10 mg 264.00 USD
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Replaces Prod. #: ALX-340-020

A major uterine luteolytic prostaglandin. Endogenous agonist of the prostanoid FP receptor (KD=1.0nM). Inhibits differentiation of 3T3-L1 preadipocytes.

Product Specification

Alternative Name:Dinoprost, 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid, PGF
 
Formula:C20H34O5
 
MW:354.5
 
CAS:551-11-1
 
Purity:≥99% (TLC)
 
Appearance:Low melting white solid or colorless oil.
 
Solubility:Soluble in 100% ethanol (50mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
 
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Product Literature References

The mechanism of inhibition of 3T3-L1 preadipocyte differentiation by prostaglandin F2alpha: C.W. Miller, et al.; Endocrinology 137, 5641 (1996), Abstract;
Cloning and expression of a cDNA for the human prostanoid FP receptor: M. Abramovitz, et al.; J. Biol. Chem. 269, 2632 (1994), Abstract;
Role of progesterone in regulating uteroovarian venous concentrations of PGF2 alpha and PGE2 during the estrous cycle and early pregnancy in ewes: D.L. Vincent & E.K. Inskeep; Prostaglandins 31, 715 (1986), Abstract;

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