Vinpocetine

PDE inhibitor



BML-PD185-0020	20 mg	50.00 USD

BML-PD185-0100	100 mg	203.00 USD

Replaces Prod. #: ALX-270-150

Selective inhibitor of Ca²⁺/calmodulin-dependent phosphodiesterase (PDE I, IC₅₀=20 µM).

Product Specification

Formula:	C₂₂H₂₆N₂O₂

MW:	350.5

Purity:	≥98%

Appearance:	White solid.

CAS:	42971-09-5

MI:	14: 9991

RTECS:	JW4792000

Solubility:	Soluble in DMSO or acetone.

Long Term Storage:	Ambient

Hazard:	HARMFUL.

Background / Technical Information:	Please click here for the comprehensive product datasheet.

Product Literature References

Modulation of TNF alpha and IL-1 beta from endotoxin-stimulated monocytes by selective PDE isozyme inhibitors: K. Molnar-Kimber, et al.; Agents Actions 39, C77 (1993), Abstract;

Cyclic 3’,5’-nucleotide diesterases in dynamics of cAMP and cGMP in rat collecting duct cells: M. Yamaki, et al.; Am. J. Physiol. 262, F957 (1992), Abstract;

Regulation of cyclic AMP metabolism in bovine adrenal medullary cells: P.D. Marley & K.A. Thomson; Biochem. Pharmacol. 44, 2105 (1992), Abstract;

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta: H.S. Ahn, et al.; Biochem. Pharmacol. 38, 3331 (1989), Abstract;

Effects of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle: M. Hagiwara, et al.; Biochem. Pharmacol. 33, 453 (1984), Abstract;