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Quazinone

PDE inhibitor
 
BML-PD170-0010 10 mg 91.00 USD
 
BML-PD170-0050 50 mg 362.00 USD
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Replaces Prod. #: ALX-270-116

Selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III, IC50=0.6µM).

Product Specification

Alternative Name:Ro 13-6438, (R)-6-Chloro-1,5-dihydro-3-methyl- imidazo[2,1-b]quinazolin-2-one
 
Formula:C11H10ClN3O
 
MW:235.7
 
CAS:70018-51-8
 
Purity:≥98% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO (3mg/ml) or 100% ethanol (1mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Stable for at least 1 year after receipt when stored at +20°C. Stock solutions are stable for up to 3 months at -20°C.
 
Technical Info/Product Notes:Note: Product is not sterile.
 
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Product Literature References

Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties: M. Holck, et al.; J. Cardiovasc. Pharmacol. 6, 520 (1984), Abstract;

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