EHNA

PDE inhibitor



BML-PD129-0010	10 mg	52.00 USD

BML-PD129-0050	50 mg	206.00 USD

Phosphodiesterase PDE II inhibitor, IC₅₀=0.8 µM. Also inhibits adenosine deaminase, K_i=4 nM.

Product Specification

Alternative Name:	Erythro-9-(2-hydroxy-3-nonyl)adenine . HCl

Formula:	C₁₄H₂₃N₅O . HCl

MW:	313.8

Purity:	≥98%

Appearance:	White solid.

CAS:	51350-19-7

Solubility:	Soluble in water (25mg/ml).

Long Term Storage:	Ambient

Background / Technical Information:	Please click here for the comprehensive product datasheet.

Product Literature References

Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes: P.F. Mery, et al.; Mol. Pharmacol. 48, 121 (1995), Abstract;

Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine: T. Podzuweit, et al.; Cell. Signal. 7, 733 (1995), Abstract;

Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition: M. Bessodes, et al.; Biochem. Pharmacol. 31, 879 (1982), Abstract;