Phosphodiesterase PDE II inhibitor, IC50=0.8 µM. Also inhibits adenosine deaminase, Ki=4 nM.
Product Specification
Product Literature References
Effect of chirality in erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) on adenosine deaminase inhibition: M. Bessodes, et al.; Biochem. Pharmacol.
31, 879 (1982),
Abstract;
Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes: P.F. Mery, et al.; Mol. Pharmacol.
48, 121 (1995),
Abstract;
Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine: T. Podzuweit, et al.; Cell. Signal.
7, 733 (1995),
Abstract;