[pTyr^1146/1150] Insulin receptor (1142-1153)

This sequence, TRDIpYETDpYYRK, is from the insulin receptor ß-subunit cytoplasmic domain, inclusive of regulatory autophosphorylation sites Tyr¹¹⁴⁶, Tyr¹¹⁵⁰ and Tyr¹¹⁵¹. The unphosphorylated version of this peptide has been used as an insulin receptor kinase substrate. The phosphorylated peptide has been used as a protein tyrosine phosphatase substrate.