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SOS-1 (human) (1149-1158)

PI3 kinase inhibitor
 
BML-P305-0001 1 mg 99.00 USD
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SH3 binding sequence of guanine nucleotide exchange factor hSOS which is a ligand for the adaptor protein Grb2 SH3 domain. Blocks SOS/Grb2 interaction and thereby prevents Ras activation via receptor protein tyrosine kinases. Km=5.6 µM for N-terminal SH3 of Grb2.

Product Specification

Alternative Name:SOS-1 (human) N10 SH3 binding domain, Ras inhibitory peptide
 
Sequence:Val-Pro-Pro-Pro-Val-Pro-Pro-Arg-Arg-Arg
 
MW:1169.7
 
Purity:≥98%
 
Appearance:Lyophilized solid.
 
Solubility:Soluble in Water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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