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MeOSuc-AAPV-AMC

Elastase substrate
 
BML-P224-0005 5 mg 87.00 USD
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Highly sensitive substrate for neutrophil elastase (leukocyte elastase) (Km=130 µM), but not granzyme H. This substrate can be used for in vitro assays with purified enzyme, on live cells, or in conditioned medium. Ex: 380 nm, Em: 460 nm.

Product Specification

Alternative Name:Neutrophil elastase substrate (fluorogenic)
 
Sequence:N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin
 
Formula:C31H41N5O9
 
MW:627.7
 
CAS:72252-90-5
 
Purity:≥95% (HPLC)
 
Appearance:White solid
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

Product Literature References

A secretory leukocyte protease inhibitor variant with improved activity against lung infection: N. Camper, et al.; Mucosal Immunol. 9, 669 (2016), Abstract;

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