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Protein kinase C (20-28) (myristoylated)

PKC inhibitor
 
BML-P205-0500 0.5 mg 116.00 USD
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Pseudosubstrate sequence from PKCα and ß. Highly specific inhibitor, which is N-terminal myristoylated to allow membrane permeability. IC50=8 µM for TPA activation of MARCKS phosphorylation in fibroblast primary cultures, and 98% inhibition at 100 µM. Partially reverses multidrug resistance in human breast cancer cells.

Product Specification

Alternative Name:PKC (20-28) (myristoylated)
 
Sequence:N-Myristoyl-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-OH
 
MW:1256.0
 
Formulation:TFA salt. Lyophilized.
 
Purity:≥98% (HPLC)
 
Solubility:Soluble in water or in 20mM TRIS-HCl, pH 7.5.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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