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CaM kinase II (281-309)

CaM kinase inhibitor
 
BML-P201-0500 0.5 mg 284.00 USD
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Sequence is from Ca2+/calmodulin-dependent kinase A subunit negative regulatory sequence containing the calmodulin binding site (290-309) plus autophosphorylation site (Thr286). Peptide can be phosphorylated at Thr286 by PKC. Useful as a CaM binding peptide and inhibits CaMKII by blocking Ca2+/CaM activation and the enzyme active-site. IC50=80 nM, CaM binding; IC50=2 µM, active-site.

Product Specification

Alternative Name:CaMKII (281-309), Ca2+/calmodulin-dependent protein kinase II (281-309)
 
Sequence:Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
 
MW:3374.5
 
Purity:≥97%
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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