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Abz-SDK(Dnp)-P

ACE substrate
 
BML-P162-0001 1 mg 109.00 USD
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Fluorogenic substrate for angiotensin converting enzyme-1 (ACE1) N-domain. The somatic form of ACE1 is a zinc-dependent peptidyl dipeptidase comprising two catalytic domains referred to as the N- and C-domains. The testicular form, due to a downstream start site, contains only the C-domain. Abz fluorescence is quenched by the Dnp group until cleavage (at Asp-Lys) separates them. Ex: 320 nm, Em: 420 nm. This quenched substrate is useful for assay of cell culture ACE1 N-domain activity, inhibitor screening and kinetic analysis.

Product Specification

Alternative Name:ACE1 (N-domain) substrate (fluorogenic)
 
Sequence:Abz-Ser-Asp-Lys(Dnp)-Pro-OH[Abz=o-aminobenzoicacid;Dnp=2,4-dinitrophenyl]
 
MW:730.9
 
Purity:≥97%
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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Angiotensin converting enzyme
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Angiotensin converting enzyme Substrate
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