This sequence, DLDVPIPGRFDRRVpSVAAE is derived from cAMP-dependent protein kinase regulatory subunit type II [PKA; [Ala-97]-RII (81-99)] with a phosphoserine at Ser95. This peptide can be used directly as a calcineurin (protein phosphatase 2B, PP2B) substrate. Phosphate release can be quantified using the (BML-AK111) detection reagent.
Product Details
| Alternative Name: | RII Phosphopeptide, [pSer95, Ala97]-cAMP-dependent protein kinase regulatory subunit type II (81-99) |
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| Sequence: | Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-pSer-Val-Ala-Ala-Glu |
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| MW: | 2192.0 |
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| Source: | Synthetic. |
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| Formulation: | Lyophilized. Trifluoroacetate salt. |
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| Purity: | ≥95% (HPLC) |
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| Identity: | Determined by MS. |
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| Appearance: | Solid. |
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| Solubility: | Soluble in water. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stock solution in water is highly stable at -20°C |
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| Handling: | Protect from moisture |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance: R.W. Baranowski, et al.; Biochem. Biophys. Res. Commun.
623, 89 (2022),
Abstract;
