Reference peptide for OMNIMMP® fluorogenic substrate (BML-P126) and TACE (ADAM17) fluorogenic substrate (BML-P132). Ex.: 328nm, Em.: 393nm. The following Ex/Em have also been used: 320-340/400-420.
Product Details
| Alternative Name: | Mca-Pro-Leu-OH |
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| Sequence: | Mca-Pro-Leu-OH [Mca=(7-methoxycoumarin-4-yl)acetyl] |
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| Formula: | C23H26N2O7 |
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| MW: | 444.5 |
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| Source: | Synthetic. |
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| CAS: | 140430-55-3 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White powder. |
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| Solubility: | Soluble in methanol (50 mg/ml) or DMSO (20 mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Stock solution in methanol is highly stable at -20°C |
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| Handling: | Protect from light and moisture. Store under inert gas. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Reduced autophagy leads to an impaired ferritin turnover in senescent fibroblasts: C. Ott, et al.; Free Radic. Biol. Med.
101, 325 (2016),
Abstract;
Disposable MMP-9 sensor based on the degradation of peptide cross-linked Hydrogel films using electrochemical impedance spectroscopy: A. Biela, et al.; Biosens. Bioelectron.
68C, 660 (2015),
Abstract;
A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases: C.G. Knight, et al.; FEBS Lett.
296, 263 (1992),
Abstract;
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