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Autocamtide-2

CaM kinase inhibitor
 
BML-P101-0001 1 mg 103.00 USD
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Replaces Prod. #: ALX-151-023

Sequence, KKALRRQETVDAL, derived from Ca2+/calmodulin-dependent protein kinase II autophosphorylation site RQETVD plus basic residues to facilitate phosphocellulose binding. Contains consensus phosphorylation sequence R-X-X-S/T. Highly selective CaMKII substrate (Km=2 µM for CaMKII; 50 µM for PKC; no activity towards PKA).

Product Specification

Identity:Determined by MS.
 
Sequence:H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH
 
Formula:C65H118N22O20
 
MW:1527.8
 
Source:Synthetic.
 
Formulation:Lyophilized.
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

Product Literature References

Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulation: P.I. Hanson, et al.; Neuron 3, 59 (1989), Abstract;

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