ORG-12962

Serotonin receptor activator



BML-NS705-0010	10 mg	82.00 USD

BML-NS705-0050	50 mg	330.00 USD

Selective serotonin 5-HT_2C agonist. Displays antiaversive effects in a panic-like anxiety rat model. May display appetite regulating properties similar to other 5-HT_2C agonists.

Product Specification

Alternative Name:	1-[6-Chloro-5-trifluoromethyl)-2-pyridinyl]-piperazine

Formula:	C₁₀H₁₁ClF₃N₃

MW:	265.7

Purity:	≥98% (TLC)

Appearance:	Pale yellow solid.

CAS:	210821-63-9

Solubility:	Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).

Long Term Storage:	+20°C

Use/Stability:	Store solutions at -20°C for up to 3 months.

Background / Technical Information:	Please click here for the comprehensive product data sheet.

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Product Literature References

Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity: J.C. Halford, et al.; Curr. Drug Targets 6, 201 (2005), Abstract;

Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells: R.H. Porter, et al.; Br. J. Pharmacol. 128, 13 (1999), Abstract;

Antiaversive effects of 5HT2C receptor agonists and fluoxetine in a model of panic-like anxiety in rats: F. Jenck, et al.; Eur. Neuropsychopharmacol. 8, 161 (1998), Abstract;