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ORG-12962

Serotonin receptor activator
 
BML-NS705-0010 10 mg 86.00 USD
 
BML-NS705-0050 50 mg 374.00 USD
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Selective serotonin 5-HT2C agonist. Displays antiaversive effects in a panic-like anxiety rat model. May display appetite regulating properties similar to other 5-HT2C agonists.

Product Specification

Alternative Name:1-[6-Chloro-5-trifluoromethyl)-2-pyridinyl]-piperazine
 
Formula:C10H11ClF3N3
 
MW:265.7
 
CAS:210821-63-9
 
Purity:≥95% (NMR)
 
Identity:Determined by 1H-NMR.
 
Appearance:Pale yellow solid.
 
Solubility:Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Store solutions at -20°C for up to 3 months.
 
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Product Literature References

Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity: J.C. Halford, et al.; Curr. Drug Targets 6, 201 (2005), Abstract;
Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells: R.H. Porter, et al.; Br. J. Pharmacol. 128, 13 (1999), Abstract;
Antiaversive effects of 5HT2C receptor agonists and fluoxetine in a model of panic-like anxiety in rats: F. Jenck, et al.; Eur. Neuropsychopharmacol. 8, 161 (1998), Abstract;

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