Highly selective histamine H2 agonist, devoid of stimulatory activity at H1 and H3 receptors. It induces a dose-dependent increase in gastric acid secretion and is a superior alternative to other H2 agonists for the study of gastric acid secretion.
Product Specification
| Alternative Name: | 2-Amino-5-(2-aminoethyl)-4-methylthiazole . 2HBr |
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| Formula: | C6H11N3S.2HBr |
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| MW: | 319.1 |
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| CAS: | 142457-00-9 |
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| Purity: | ≥99% (HPLC) |
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| Appearance: | Cream crystalline solid |
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| Solubility: | Soluble in water. |
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| Shipping: | Ambient |
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| Long Term Storage: | -20°C |
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Product Literature References
In vitro cardiac pharmacology of the new histamine H2-receptor agonist amthamine: comparisons with histamine and dimaprit: E. Poli, et al.; Agents Actions
40, 44 (1993),
Abstract;
The new potent and selective histamine H2 receptor agonist amthamine as a tool to study gastric secretion: G. Coruzzi, et al.; Nauyn Schmeidebergs Arch. Pharmacol.
348, 77 (1993),
Abstract;
Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles: J. C. Eriks, et al.; J. Med. Chem
35, 3239 (1992),
Abstract;
