Benzamil . HCl

Na⁺ channel blocker



BML-NA103-0050	50 mg	135.00 USD

Replaces Prod. #: ALX-550-235

Derivative of amiloride (Prod. No. BML-CA200). Potent sodium channel blocker.

Product Specification

Alternative Name:	Benzylamiloride . HCl, N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide . HCl

Formula:	C₁₃H₁₄ClN₇O·HCl

MW:	356.2

Purity:	≥98% (TLC)

Appearance:	Yellow solid.

CAS:	2898-76-2

Solubility:	Soluble in water.

Long Term Storage:	Ambient

Use/Stability:	Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.

Hazard:	IRRITANT.

Handling:	Protect from light.

Background / Technical Information:	Please click here for the comprehensive product datasheet.

Product Literature References

Regulation of brain renin-angiotensin system by benzamil-blockable sodium channels: M. Nishimura, et al.; Am. J. Physiol. 276, R1416 (1999), Abstract;

Modulation of cardiac performance by amiloride and several selected derivatives of amiloride: G.N. Pierce, et al.; J. Pharmacol. Exp. Ther. 265, 1280 (1993), Abstract;

Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes: J.W. Lane, et al.; Br. J. Pharmacol. 106, 283 (1992), Abstract;

Amiloride and its analogs as tools in the study of ion transport: T.R. Kleyman & E.J. Cragoe; J. Membr. Biol. 105, 1 (1988), Abstract;