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Benzamil . HCl

Na+ channel blocker
 
BML-NA103-0050 50 mg 210.00 USD
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Replaces Prod. #: ALX-550-235

Derivative of amiloride (Prod. No. BML-CA200). Potent sodium channel blocker.

Product Specification

Alternative Name:Benzylamiloride . HCl, N-(Benzylamidino)-3,5-diamino-6-chloropyrazinecarboxamide . HCl
 
Formula:C13H14ClN7O . HCl
 
MW:356.2
 
CAS:2898-76-2
 
Purity:≥98% (HPLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at room temperature. Stock solutions are stable for up to 3 months at -20°C.
 
Handling:Protect from light.
 
BML-NA103 structure
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BML-NA103 structure

Product Literature References

Regulation of brain renin-angiotensin system by benzamil-blockable sodium channels: M. Nishimura, et al.; Am. J. Physiol. 276, R1416 (1999), Abstract;
Modulation of cardiac performance by amiloride and several selected derivatives of amiloride: G.N. Pierce, et al.; J. Pharmacol. Exp. Ther. 265, 1280 (1993), Abstract;
Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes: J.W. Lane, et al.; Br. J. Pharmacol. 106, 283 (1992), Abstract;
Amiloride and its analogs as tools in the study of ion transport: T.R. Kleyman & E.J. Cragoe; J. Membr. Biol. 105, 1 (1988), Abstract;

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Sodium channel
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Sodium channel Blocker
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