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Nicotinamide

 
BML-KI283-0500 500 µl 45.00 USD
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Replaces Prod. #: ALX-460-008

Nicotinamide, the water-soluble amide of nicotinic acid, is a component of the two most important coenzymes - nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate. Thus nicotinamide is involved in numerous oxidation-reduction reactions in mammalian biological systems acting as an antioxidant.

Product Details

Formula:C6H6N2
 
MW:122.1
 
CAS:98-92-0
 
MI:14: 6523
 
Formulation:50 mM Nicotinamide in 50 mM Tris/Cl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl2.
 
Appearance:Clear solution.
 
Solubility:Soluble in water, 100% ethanol or glycerol. Slightly soluble in chloroform, almost insoluble in ether or acetone.
 
Shipping:Blue Ice
 
Long Term Storage:-80°C
 
Use/Stability:Store, as supplied, at -70°C for up to 1 year.
 
Regulatory Status:RUO - Research Use Only
 
460-008
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460-008

Product Literature References

Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site: P. Mellini, et al.; J. Med. Chem. 62, 5844 (2019), Abstract;
Two Novel Proline-Containing Catechin Glucoside from Water-Soluble Extract of Codonopsis pilosula: F.Y. Qin, et al.; Molecules 23, E180 (2018), Application(s):SIRT1 Inhibition, Abstract; Full Text
Histone deacetylase (HDAC) 1 controls the expression of beta defensin 1 in human lung epithelial cells: K. Kallsen, et al.; PLoS One 7, e50000 (2012), Abstract; Full Text

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