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Charybdotoxin, (recombinant)

K+ channel blocker
 
BML-KC168-0100 100 µg 374.00 USD
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Charybdotoxin was originally isolated from the venom of the Israeli scorpion Leiurus quinquestriatus hebraeus. Charybdotoxin blocks KCa1.1 (large conductance Ca2+ activated K+, Slo) channels in nanomolar concentrations as as well as Kv1.2 (Kd, 14 nM) and Kv1.3 (Kd, 2.6 nM) channels.). However, experiments with cloned KCa1.1 channels demonstrate the strong effect of the slob subunits on the potency of block by Charybdotoxin. This product is a recombinant peptide expressed in and extracted from E. coli.

Product Specification

Sequence:Gln-Phe-Thr-Asn-Val-Ser-Cys-Thr-Thr-Ser-Lys-Glu-Cys-Trp-Ser-Val-Cys-Gln-Arg-Leu-His-Asn-Thr-Ser-Arg-Gly-Lys-Cys-Met-Asn-Lys-Lys-Cys-Arg-Cys-Tyr-Ser
 
MW:4313
 
CAS:95751-30-7
 
Purity:≥98%
 
Appearance:Lyophilized solid.
 
Solubility:Soluble in Water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 

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