α-Dendrotoxin

K⁺ channel blocker



BML-KC167-0140	140 µg	414.00 USD

α-Dendrotoxin is isolated from Dendroaspis angusticeps snake venom, by modification of the procedures of Harvey and Benishin and purified to homogeneity. α-Dendrotoxin blocks K_v1.1 and K_v1.2 channels (IC₅₀= 0.4 to 4 and 1.1 to 12 nM in oocytes respectively, with higher values for mammalian cells). In addition, the toxin was shown to block also K_v1.6 (IC₅₀= 9-25 nM).

Product Specification

MW:	7048.1

Purity:	98%

Appearance:	Lyophilized solid.

Sequence:	Gln-Pro-Arg-Arg-Lys-Leu-Cys-Ile-Leu-His-Arg-Asn-Pro-Gly-Arg-Cys-Tyr-Asp-Lys-Ile-Pro-Ala-Phe-Tyr-Tyr-Asn-Gln-Lys-Lys-Lys-Gln-Cys-Glu-Arg-Phe-Asp-Trp-Ser-Gly-Cys-Gly-Gly-Asn-Ser-Asn-Arg-Phe-Lys-Thr-Ile-Glu-Glu-Cys-Arg-Arg-Thr-Cys-Ile-Gly

CAS:	74504-53-3

Solubility:	Soluble in Water.

Long Term Storage:	-20°C

Hazard:	VERY TOXIC.

Background / Technical Information:	Please click here for the comprehensive product datasheet.