Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid

R527 ligand
 
BML-K005-0050 50 µg 177.00 USD
Do you need bulk/larger quantities?
 
Stimulates neutrophil degranulation and Ca2+ mobilization by a mechanism independent of the LTB4 receptor. Has been shown to act as an agonist at a G protein-coupled receptor (R527). Induces the infiltration of granulocytes into human skin.

Product Specification

Formula:C20H30O3
 
MW:318.5
 
CAS:106154-18-1
 
Concentration:50 µg/ml
 
Formulation:Oil dissolved in ethanol
 
Purity:≥95% (HPLC)
 
Appearance:Liquid.
 
Shipping:Shipped on Dry Ice
 
Long Term Storage:-80°C
 
Use/Stability:Store, as supplied, at -80°C for up to 1 year.
 
bml-k005
Please mouse over
bml-k005

Product Literature References

5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin: S. Muro, et al.; J. Allergy Clin. Immunol. 112, 768 (2003), Abstract;
Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils: C.E. Jones, et al.; Mol. Pharmacol. 63, 471 (2003), Abstract; Full Text
5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration: W.S. Powell, et al.; J. Immunol. 154, 4123 (1995), Abstract;
5-Oxo-eicosanoids are potent eosinophil chemotactic factors. Functional characterization and structural requirements: U. Schwenk & J.M. Schroeder ; J. Biol. Chem. 270, 15029 (1995), Abstract;
Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils: W.S. Powell, et al.; J. Lipid Res. 36, 2590 (1995), Abstract; Full Text
5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus: J.T. O'Flaherty, et al.; Biochem. Biophys. Res. Commun. 192, 129 (1993), Abstract;

Related Literature

Brochures
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Comprehensive Tools for Quantifying Cellular Responses to Oxidative Damage
Download as PDF

Technical Posters
Arachidonic Acid Metabolites
Arachidonic Acid Metabolites
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,