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α-Hydroxytriazolam

An active but short-lived metabolite of triazolam
 
BML-J130-0001 1 mg 133.00 USD
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Metabolite of triazolam.

Product Specification

Alternative Name:8-Chloro-6-(o-chlorophenyl)-4H-s-Triazolo[4,3-a][1,4]-benzodiazepine-1-methanol
 
Formula:C17H12Cl2N4O
 
MW:359.2
 
CAS:37115-45-0
 
Purity:≥96% (TLC)
 
Identity:Determined by 1H-NMR and MS.
 
Appearance:White solid.
 
Solubility:Soluble in DMSO (5mg/ml warm) or methanol (1mg/ml warm).
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
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Product Literature References

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole: L. L. von Moltke, et al.; J. Pharmacol. Exp. Ther. 276, 370 (1996), Abstract;
Immunoassay detection of benzodiazepines and benzodiazepine metabolites in blood: W. Huang & D.E. Moody; J. Anal. Toxicol. 19, 333 (1995), Abstract;
Triazolam: a review of its pharmacological properties and therapeutic efficacy in patients with insomnia: G. E. Pakes, et al.; Drugs 22, 81 (1981), Abstract;
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines: M. Gall, et al.; J. Med. Chem. 21, 1290 (1978), Abstract;

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